Details
Chemical plants supply high-quality 2-Naphthylhydrazine hydrochloride 2243-58-5 in bulk
- Molecular Formula:C10H10N2.HCl
- Molecular Weight:194.664
- Vapor Pressure:1.87E-05mmHg at 25°C
- Melting Point:123 °C
- Boiling Point:362.9 °C at 760 mmHg
- Flash Point:203.9 °C
- PSA：38.05000
- Density:1.215g/cm3
- LogP:3.70070
2-Naphthylhydrazine hydrochloride(Cas 2243-58-5) Usage
InChI:InChI=1/C10H10N2.ClH/c11-12-10-6-5-8-3-1-2-4-9(8)7-10;/h1-7,12H,11H2;1H
2243-58-5 Relevant articles
Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors
Haffner, Curt D.,Charnley, Adam K.,Aquino, Christopher J.,Casillas, Linda,Convery, Máire A.,Cox, Julie A.,Elban, Mark A.,Goodwin, Nicole C.,Gough, Peter J.,Haile, Pamela A.,Hughes, Terry V.,Knapp-Reed, Beth,Kreatsoulas, Constantine,Lakdawala, Ami S.,Li, Huijie,Lian, Yiqian,Lipshutz, David,Mehlmann, John F.,Ouellette, Michael,Romano, Joseph,Shewchuk, Lisa,Shu, Arthur,Votta, Bartholomew J.,Zhou, Huiqiang,Bertin, John,Marquis, Robert W.
supporting information, p. 1518 - 1523 (2019/10/19)
Herein we report the discovery of pyrazo...
A 10 - bromo - 7H - benzo [c] carbazole preparation method (by machine translation)
-
Paragraph 0091; 0095, (2019/10/17)
The invention discloses a 10 - bromo - 7...
Synthesis of Aryl Hydrazines via CuI/BMPO Catalyzed Cross-Coupling of Aryl Halides with Hydrazine Hydrate in Water
Kumar, Siripuram Vijay,Ma, Dawei
supporting information, p. 1003 - 1006 (2018/09/20)
The N,N’-bis(2,6-dimethylphenyl)oxalamid...
Asymmetric catalysis on the nanoscale: The organocatalytic approach to helicenes
Koetzner, Lisa,Webber, Matthew J.,Martinez, Alberto,Defusco, Claudia,List, Benjamin
supporting information, p. 5202 - 5205 (2014/05/20)
The first asymmetric organocatalytic syn...
2243-58-5 Process route
-
-
91-59-8
naphthalen-2-ylamine
-
-
2243-58-5
2-naphthylhydrazine hydrochloride
| Conditions | Yield |
|---|---|
|
naphthalen-2-ylamine;
With
hydrogenchloride; sodium nitrite;
In
water;
for 1h;
Cooling with ice;
With
tin(ll) chloride;
In
water;
for 3.5h;
Cooling with ice;
|
63% |
|
With
hydrogenchloride; tin(ll) chloride; sodium nitrite;
Multistep reaction;
1.) -5 deg C to 0 deg C, 0.75 h, 2.) 1 h;
|
|
|
naphthalen-2-ylamine;
With
hydrogenchloride; sodium nitrite;
In
water;
at 0 ℃;
for 0.416667h;
With
hydrogenchloride; tin(ll) chloride;
In
water;
at 0 ℃;
for 0.5h;
|
|
|
naphthalen-2-ylamine;
With
hydrogenchloride; sodium nitrite;
In
water;
at -5 - 0 ℃;
for 0.5h;
With
tin(ll) chloride;
In
water;
at 0 - 20 ℃;
|
-
-
580-13-2
2-bromonaphthalene
-
-
2243-58-5
2-naphthylhydrazine hydrochloride
| Conditions | Yield |
|---|---|
|
2-bromonaphthalene;
With
potassium phosphate; copper(l) iodide; N,N′-bis(2,6-dimethylphenyl)oxalamide; cetyltrimethylammonim bromide;
In
water;
at 80 ℃;
for 0.25h;
Schlenk technique;
Inert atmosphere;
Sealed tube;
With
hydrazine hydrate;
In
water;
at 80 ℃;
Inert atmosphere;
Schlenk technique;
Sealed tube;
With
hydrogenchloride;
In
water;
pH=3 - 4;
Inert atmosphere;
Schlenk technique;
Sealed tube;
|
70% |
|
Multi-step reaction with 2 steps
1.1: s-BuLi / tetrahydrofuran; cyclohexane / 0.5 h / -78 °C
1.2: tetrahydrofuran; cyclohexane / -78 - 20 °C
2.1: HCl / dioxane; propan-2-ol / 0.5 h / 60 °C
With
hydrogenchloride; sec.-butyllithium;
In
tetrahydrofuran; 1,4-dioxane; cyclohexane; isopropyl alcohol;
|
2243-58-5 Upstream products
-
91-59-8
naphthalen-2-ylamine
-
868394-40-5
di-tert-butyl 1-(naphthalene-2-yl)hydrazine-1,2-dicarboxylate
-
580-13-2
2-bromonaphthalene
-
135-19-3
β-naphthol
2243-58-5 Downstream products
-
63039-88-3
9-methyl-12,13-dihydro-7H-dibenzo[a,g]carbazole
-
55970-05-3
2,3-dimethylbenz<4,5>indole
-
21064-52-8
7,8,9,11-tetrahydrobenzo[c]carbazole
-
194-59-2
7H-dibenzo[c,g]carbazole
Related Products
-
Benzaldehyde-2,4-disulfonic acid disodium saltCAS：33513-44-9
-
prednisolone 21-(3-sodium-sulphobenzoate)CAS：630-67-1
-
