4-HYDROXYTAMOXIFEN

  • CAS:68047-06-3
  • purity:99%
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Quality products?make an important contribution to long-term revenue and profitability. High quality purity >99% 4-HYDROXYTAMOXIFEN 68047-06-3 for sale

1.What is the 4-HYDROXYTAMOXIFEN ?

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4-Hydroxytamoxifen, a hydroxylated analogue of tamoxifen, is a metabolite of tamoxifen with anti-estrogenic properties. It plays a significant role in the therapeutic effects of tamoxifen, a selective estrogen receptor modulator used in the treatment of breast cancer.
Used in Pharmaceutical Industry:
4-Hydroxytamoxifen is used as an active metabolite for the treatment of breast cancer. It exhibits anti-estrogenic properties, which help in blocking the effects of estrogen, a hormone that promotes the growth of breast cancer cells. Its role in tamoxifen's therapeutic effects makes it a crucial component in the management of hormone receptor-positive breast cancer.
Used in Research Applications:
4-Hydroxytamoxifen is used as a research tool for studying the mechanisms of action of tamoxifen and its effects on estrogen receptor-positive breast cancer cells. It aids in understanding the anti-estrogenic properties and the role of metabolites in the therapeutic efficacy of tamoxifen.
Used in Drug Development:
4-Hydroxytamoxifen serves as a starting point for the development of new drugs with improved anti-estrogenic properties and fewer side effects. Its structural and functional characteristics provide valuable insights for the design and synthesis of novel compounds targeting estrogen receptor-positive breast cancer.

2.What is the CAS number for 4-HYDROXYTAMOXIFEN ?

The CAS number of 4-HYDROXYTAMOXIFEN is 68047-06-3.

3.What are another words for 4-HYDROXYTAMOXIFEN ?

Synonyms?for?4-HYDROXYTAMOXIFEN 68047-06-3:Phenol,4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]- (9CI); Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, (Z)-;(Z)-4-Hydroxytamoxifen; 4-Hydroxy-(Z)-tamoxifen; 4-Hydroxytamoxifen;4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol;Hydroxytamoxifen; ICI 79280; trans-4-Hydroxytamoxifen; trans-Hydroxytamoxifen

4.What is 4-HYDROXYTAMOXIFEN (68047-06-3) used for?

tamoxifen metabolite, anti-estrogen, see Tamoxifen 1,01038

InChI:InChI=1/C26H29NO2/c1-4-25(20-10-14-23(28)15-11-20)26(21-8-6-5-7-9-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-

Relevant articles related to 4-HYDROXYTAMOXIFEN:

Article

Source

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development for screening of potential tamoxifen-drug/herb interaction via in vitro cytochrome P450 inhibition assay

Liew, Mervyn W. O.,Tan, S. C.,Yaacob, N. S.,Yong, Y. F.

, (2020/05/22)

Methods for Determining the Oncogenic Condition of Cell, Uses Thereof, and Methods for Treating Cancer

-

, (2017/07/14)

Photochemical Activation of Tertiary Amines for Applications in Studying Cell Physiology

Asad, Naeem,Deodato, Davide,Lan, Xin,Widegren, Magnus B.,Phillips, David Lee,Du, Lili,Dore, Timothy M.

supporting information, p. 12591 - 12600 (2017/09/23)

5.Buy 4-HYDROXYTAMOXIFEN with the best price .

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